Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. RRM1, ribonucleotide reductase M1
Sequence ID:NM_001033
RefSeqGene ID:NG_027992
Entrez Gene ID:6240
Ensembl ID:ENSG00000167325

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:11p15.5Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 4116034 - 4159650

 Exon Info From UCSC:
NM_001033

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2989344Full LengthBC006498ribonucleotide reductase M1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001024  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001033 NP_001024 P23921 EC 1.17.4.1 Ribonuc_red_lgN
Ribonuc_red_lgC
ATP-cone

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC006498 AAH06498 P23921 EC 1.17.4.1
DQ893028 ABM83954    
DQ896272 ABM87271    
AK222786 BAD96506 Q53GZ5  
AK297988 BAG60296 B4DNN4  
AK299629 BAG61557 B4DS95  
AK301891 BAG63322 B4DXB0  
AK301922 BAG63343 B4DXD1  
AK303394 BAG64450 B4E0I8  
X59543 CAA42118 P23921 EC 1.17.4.1
X59617 CAA42180 P23921 EC 1.17.4.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens RRM1 NP_001024 M.musculus Rrm1 20133 Gene Info NP_033129 98
A.gambiae AgaP_AGAP010198 1279619   XP_554103 78
C.elegans rnr-1 176301   NP_499039 75
D.melanogaster RnrL 34392   NP_477027 75
N.crassa NCU03539 3872956   XP_956818 74
S.pombe cdc22 2541695   NP_594491 71
A.thaliana RNR1 816715   NP_179770 69
S.cerevisiae RNR1 856801   NP_010993 68
P.falciparum PF14_0352 811934   XP_001348526 67
S.cerevisiae RNR3 854744   NP_012198 67

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)