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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. RPS6KA3, ribosomal protein S6 kinase, 90kDa, polypeptide 3
Sequence ID:NM_004586
RefSeqGene ID:NG_007488
Entrez Gene ID:6197
Ensembl ID:ENSG00000177189

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
COFFIN-LOWRY SYNDROME 
MENTAL RETARDATION, X-LINKED19 

Cytogenetic Location (from UniGene)

Cytogenetic Location:Xp22.2-p22.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:X: 20173515 - 20284709

 Exon Info From UCSC:
NM_004586

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40007452Full LengthBC096301ribosomal protein S6 kinase, 90kDa, polypeptide 3
40007453Full LengthBC096302ribosomal protein S6 kinase, 90kDa, polypeptide 3
40007456Full LengthBC096303ribosomal protein S6 kinase, 90kDa, polypeptide 3

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004577  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_004586 NP_004577 P51812 EC 2.7.11.1 Pkinase
Pkinase_C

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U08316 AAA81952 P51812 EC 2.7.11.1
L07599 AAC82495 P51812 EC 2.7.11.1
BC096301 AAH96301 P51812 EC 2.7.11.1
BC096302 AAH96302 P51812 EC 2.7.11.1
BC096303 AAH96303 P51812 EC 2.7.11.1
AB102662 BAC81131 P51812 EC 2.7.11.1
AB208933 BAD92170 P51812 EC 2.7.11.1
AK313932 BAG36651 P51812 EC 2.7.11.1
AK294373 BAG57633 B4DG22  
AK296775 BAG59354 B4DKZ2  
AK316482 BAH14853 B7ZB17  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens RPS6KA3 NP_004577 M.musculus Rps6ka3 110651 Gene Info NP_683747 100
R.norvegicus Rps6ka3 501560   XP_576965 100
A.gambiae AgaP_AGAP003040 1272910   XP_311835 67
D.melanogaster S6kII 33139   NP_523437 63

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta