Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. TLK2, tousled-like kinase 2
Sequence ID:NM_001112707
Entrez Gene ID:11011
Ensembl ID:ENSG00000146872

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q23Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 60558483 - 60690846

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3866469IncompleteBC013736tousled-like kinase 2
5297746IncompleteBC044925tousled-like kinase 2
5811061IncompleteBC060511tousled-like kinase 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006843  

Protein Infomation

NM_001112707 NP_001106178    
NM_006852 NP_006843   Pkinase

Related Sequences

AF162667 AAF03095 Q86UE8 EC
BC044925 AAH44925 Q86UE8 EC
AB004884 BAA20561 Q86UE8 EC
AK300586 BAG62284 B4DUC2  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens TLK2 NP_006843 M.musculus Tlk2 24086 Gene Info NP_001106176 99
R.norvegicus Tlk2 303592   XP_221023 99
A.gambiae AgaP_AGAP000043 1272234   XP_311117 65
D.melanogaster tlk 318206   NP_001138153 64
C.elegans tlk-1 176369   NP_499145 51
A.thaliana TSL 832217   NP_568405 51

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)