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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. SDHC, succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
Sequence ID:NM_001035511
NM_001035512
NM_001035513
NM_003001
RefSeqGene ID:NG_012767
Entrez Gene ID:6391
Ensembl ID:ENSG00000143252

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
GASTROINTESTINAL STROMAL TUMORKIT
PDGFRA
SDHB
PARAGANGLIOMA AND GASTRIC STROMAL SARCOMASDHB
SDHD
PARAGANGLIOMAS 3 

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q23.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 161284177 - 161332223

 Exon Info From UCSC:
NM_001035511
NM_001035512
NM_001035513
NM_003001

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4291847Full LengthBC020808succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
5301907Full LengthBC066329succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
5416956Full LengthBC033626succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002992  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001035511 NP_001030588    
NM_001035512 NP_001030589    
NM_001035513 NP_001030590    
NM_003001 NP_002992 Q99643 Sdh_cyt

Related Sequences

 
mRNAGenPeptSwissProt
U57877 AAB41838 Q99643
BC020808 AAH20808 Q99643
BC033626 AAH33626 Q99643
BC066329 AAH66329 Q99643
D49737 BAA31998 Q99643
AB201252 BAE46977 Q99643
AB211234 BAE46978 Q99643
AB211235 BAE46979 Q99643
AB212048 BAE46980 Q99643
AK293687 BAG57126 B4DEL5
AK294305 BAG57586 Q99643
CR457102 CAG33383 Q6IAQ2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SDHC NP_002992 R.norvegicus Sdhc 289217   NP_001005534 82
M.musculus Sdhc 66052 Gene Info NP_079597 80
D.melanogaster SdhC 41340   NP_650047 42
A.gambiae AgaP_AGAP010672 1272475   XP_311387 41

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta