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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PFKFB1, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Sequence ID:NM_002625
RefSeqGene ID:NG_013254
Entrez Gene ID:5207
Ensembl ID:ENSG00000158571

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:Xp11.21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:X: 54959566 - 55024967

 Exon Info From UCSC:
NM_002625

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40000710Full LengthBC0960776-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
40000711Full LengthBC0960786-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
40000713Full LengthBC0960796-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002616  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001271804 NP_001258733      
NM_001271805 NP_001258734      
NM_002625 NP_002616 P16118 EC 2.7.1.105
EC 3.1.3.46
PGAM
6PF2K

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M19938 AAA35818 P16118 EC 2.7.1.105
EC 3.1.3.46
BC096077 AAH96077 Q4VBA9  
BC096078 AAH96078 Q4VBA8  
BC096079 AAH96079 P16118 EC 2.7.1.105
EC 3.1.3.46
JQ425694 AFJ19239 I1Z9G3  
JQ425695 AFJ19240 I1Z9G4  
AK314089 BAG36785 P16118 EC 2.7.1.105
EC 3.1.3.46
AK300724 BAG62397 B4DUN5  
X52638 CAA36861 P16118 EC 2.7.1.105
EC 3.1.3.46

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PFKFB1 NP_002616 M.musculus Pfkfb1 18639 Gene Info NP_032850 95
R.norvegicus Pfkfb1 24638   NP_036753 95

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)