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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MCM6, minichromosome maintenance complex component 6
Sequence ID:NM_005915
RefSeqGene ID:NG_008958
Entrez Gene ID:4175
Ensembl ID:ENSG00000076003

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
LACTASE PERSISTANCE/NONPERSISTANCELCT

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 136602159 - 136634003

 Exon Info From UCSC:
NM_005915

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5122786Full LengthBC032374minichromosome maintenance complex component 6

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005906  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_005915 NP_005906 Q14566 EC 3.6.4.12 MCM

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U46838 AAC50766 Q14566 EC 3.6.4.12
BC032374 AAH32374 Q14566 EC 3.6.4.12
D84557 BAA12699 Q14566 EC 3.6.4.12
AK312575 BAG35469 Q14566 EC 3.6.4.12
AK299236 BAG61268 B4DRF6  
AK303455 BAG64499 B4E0N7  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MCM6 NP_005906 M.musculus Mcm6 17219 Gene Info NP_032593 96
R.norvegicus Mcm6 29685   NP_058983 96
A.gambiae MCM6_ANOGA 1279642   XP_319406 67
D.melanogaster Mcm6 31603   NP_511065 64
C.elegans mcm-6 176385   NP_001023011 57
N.crassa NCU05194 3878357   XP_962193 51
S.cerevisiae MCM6 852673   NP_011314 50
S.pombe mcm6 2540784   NP_596614 49
A.thaliana MCM6 834492   NP_680393 48

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta