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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. SOD1, superoxide dismutase 1, soluble
Sequence ID:NM_000454
RefSeqGene ID:NG_008689
Entrez Gene ID:6647
Ensembl ID:ENSG00000142168

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:21q22.11Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:21: 33032003 - 33040891

NM_000454 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3140145Full LengthBC001034superoxide dismutase 1, soluble

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000445  

Protein Infomation

NM_000454 NP_000445 P00441 EC Sod_Cu

Related Sequences

BC001034 AAH01034 P00441 EC
AY049787 AAL15444 P00441 EC
BT006676 AAP35322 P00441 EC
AY450286 AAR21563 P00441 EC
EF143990 ABL96474 A1YYW4  
EF151142 ABL96616 P00441 EC
AK312116 BAG35052 P00441 EC
X02317 CAA26182 P00441 EC
CR450355 CAG29351 P00441 EC
CR541742 CAG46542 P00441 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens SOD1 NP_000445 M.musculus Sod1 20655 Gene Info NP_035564 84
R.norvegicus Sod1 24786   NP_058746 83
D.melanogaster Sod 39251   NP_476735 62
A.gambiae CUSOD3 1272692   XP_311594 59
C.elegans sod-1 174141   NP_001021956 58
S.pombe sod1 2542128   NP_593163 57
C.elegans sod-5 173776   NP_494779 56
N.crassa NCU02133 3880431   XP_964291 56
S.cerevisiae SOD1 853568   NP_012638 56
A.thaliana CSD1 837405   NP_001077494 55

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta