Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. TXNRD2, thioredoxin reductase 2
Sequence ID:NM_006440
NM_145747
NM_145748
RefSeqGene ID:NG_011835
Entrez Gene ID:10587
Ensembl ID:ENSG00000184470

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:22q11.21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:22: 19863039 - 19929326


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5213425Full LengthBC099923thioredoxin reductase 2
40125905Full LengthBC117354thioredoxin reductase 2
3833751IncompleteBC007489thioredoxin reductase 2
4823296IncompleteBC032029thioredoxin reductase 2

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_006440 NP_006431 Q9NNW7 EC 1.8.1.9  

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF106697 AAD19597 Q9NNW7 EC 1.8.1.9
AF044212 AAD25167 Q9NNW7 EC 1.8.1.9
AF171054 AAD51324 Q9NNW7 EC 1.8.1.9
AF166126 AAF21431 Q9NNW7 EC 1.8.1.9
AF166127 AAF21432 Q9NNW7 EC 1.8.1.9
AF201385 AAG47635 Q9NNW7 EC 1.8.1.9
BC007489 AAH07489 Q9NNW7 EC 1.8.1.9
BC099923 AAH99923 A4FTY4  
BC117354 AAI17355 Q17RE6  
AB019694 BAA77601 Q9NNW7 EC 1.8.1.9
AB019695 BAA77602 Q9NNW7 EC 1.8.1.9
AB051439 BAB33322 Q9BYA8  
AB209724 BAD92961 Q59ET7  
AK097708 BAG53517 B3KUQ5  
BX957216 CAF29507 Q6M1B7  
CR749428 CAH18266 Q6M1B7  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens TXNRD2 NP_006431 M.musculus Txnrd2 26462 Gene Info NP_038739 85
R.norvegicus Txnrd2 50551   NP_072106 83
A.gambiae TRXR 1271658   XP_310514 59
D.melanogaster Trxr-2 40475   NP_524216 56
D.melanogaster Trxr-1 31760   NP_727252 55
C.elegans trxr-2 176259   NP_498971 50

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)