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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. SREBF2, sterol regulatory element binding transcription factor 2
Sequence ID:NM_004599
Entrez Gene ID:6721
Ensembl ID:ENSG00000198911

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:22q13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:22: 42286954 - 42288651

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5497929Full LengthBC051385sterol regulatory element binding transcription factor 2
6169568Full LengthBC056158sterol regulatory element binding transcription factor 2
5498684IncompleteBC051799sterol regulatory element binding transcription factor 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004590  

Protein Infomation

NM_004599 NP_004590 Q12772 HLH

Related Sequences

U02031 AAA50746 Q12772
BC051385 AAH51385 Q05BD5
BC051799 AAH51799 Q12772
BC056158 AAH56158 Q12772
AK299914 BAG61752 B4DSU0
AL834221 CAD38902 Q8NCY3
CT841522 CAJ86452 Q12772
CU013184 CAK54615  
CU013472 CAK54914  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens SREBF2 NP_004590 M.musculus Srebf2 20788 Gene Info NP_150087 93
R.norvegicus Srebf2 300095   NP_001028866 93

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta