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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. POLR2L, polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
Sequence ID:NM_021128
Entrez Gene ID:5441
Ensembl ID:ENSG00000177700

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssemblies

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pineal gland, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, stem cell, stomach, synovium, t-cell, testis, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:11p15Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 840203 - 842519

NM_021128 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
51809839721840479
810925842413842528

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2958832Full LengthBC018649polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
4045138Full LengthBC005903polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_066951  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_021128 NP_066951 P62875 RNA_pol_N

Related Sequences

 
mRNAGenPeptSwissProt
U37690 AAA91459 P62875
BC005903 AAH05903 P62875
BC018649 AAH18649 P62875
DQ893146 ABM84072  
DQ896440 ABM87439  
DQ896562 ABM87561  
AK311997 BAG34935 P62875
CR536565 CAG38802 P62875

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens POLR2L NP_066951 R.norvegicus Polr2l 502374   NP_001137383 100
M.musculus Gm10774 100043714   XP_001480824 99
A.gambiae AgaP_AGAP011761 1280879   XP_320749 96
D.melanogaster Rpb10 42942   NP_651280 93
C.elegans rpb-10 171763   NP_490923 85
A.thaliana NRPB10 837690   NP_849640 81

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)