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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. ITGA4, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
Sequence ID:NM_000885
Entrez Gene ID:3676
Ensembl ID:ENSG00000115232

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q31.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 182339917 - 182402466

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100062220Full LengthBC156712integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
4342576IncompleteBC016671integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
100015216BC146277integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000876  

Protein Infomation

NM_000885 NP_000876 P13612 Integrin_alpha

Related Sequences

L12002 AAB59613 P13612
BC016671 AAH16671 Q6PJE7
BC055419 AAH55419 Q7Z4L6
BC080190 AAH80190 Q68EM9
BC146277 AAI46278 P13612
BC156712 AAI56713  
AB208885 BAD92122 Q59H74
AK303220 BAG64307 B4E045
AK303478 BAG64514 B4E0Q2
X16983 CAA34852 P13612
AJ504733 CAD43289 Q8IU66
AJ508356 CAD48165 Q8IU66
AJ510246 CAD53326 Q8IUA2
AJ510247 CAD53327 Q8IUA2
AJ510248 CAD53328 Q8IU71
AJ510249 CAD53329 Q8IU71

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens ITGA4 NP_000876 M.musculus Itga4 16401 Gene Info NP_034706 85
R.norvegicus Itga4 311144   NP_001101207 84

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta