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Gene Info

Gene Information For:Hs. SDHA, succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
Sequence ID:NM_004168
RefSeqGene ID:NG_012339
Entrez Gene ID:6389
Ensembl ID:ENSG00000073578

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
CARDIOMYOPATHY, DILATED, 1GG 
LEIGH SYNDROMEBCS1L
COX15
DLD
FOXRED1
NDUFA10
NDUFA12
NDUFA2
NDUFA9
NDUFAF2
NDUFAF6
NDUFS3
NDUFS4
NDUFS7
NDUFS8
NDUFV1
SURF1
MITOCHONDRIAL RESPIRATORY CHAIN COMPLEXII DEFICIENCYSDHAF1
PARAGANGLIOMAS 5 

Cytogenetic Location (from UniGene)

Cytogenetic Location:5p15Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 218451 - 256794

 Exon Info From UCSC:
NM_004168

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3051442Full LengthBC001380succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
3138724Full LengthBC041016succinate dehydrogenase complex, subunit A, flavoprotein (Fp)

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_004168 NP_004159 P31040 EC 1.3.5.1  

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L21936 AAA20683 P31040 EC 1.3.5.1
BC001380 AAH01380 P31040 EC 1.3.5.1
BC041016 AAH41016 Q8IW48  
DQ402982 ABD77315 Q0QF12  
D30648 BAA06332 P31040 EC 1.3.5.1
AB208991 BAD92228 Q59GW8  
AK291311 BAF84000 P31040 EC 1.3.5.1
AK094879 BAG52946 B3KT34  
AK131350 BAG54767 B3KYA5  
AK295937 BAG58722 B4DJ60  
AK302524 BAG63797 B4DYN5  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SDHA NP_004159 M.musculus Sdha 66945 Gene Info NP_075770 95
R.norvegicus Sdha 157074   NP_569112 95
A.gambiae AgaP_AGAP010429 1272618   XP_311518 78
D.melanogaster SdhA 37228   NP_725882 75
C.elegans sdha-1 181108   NP_509446 73
C.elegans sdha-2 172968   NP_492798 72
A.thaliana SDH1-1 836809   NP_201477 71
S.cerevisiae YJL045W 853405   NP_012490 68
P.falciparum PF10_0334 810491   XP_001347618 66

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta