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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. LAMB2, Laminin, beta 2 (laminin S)
Sequence ID:NM_002292
RefSeqGene ID:NG_008094
Entrez Gene ID:3913
Ensembl ID:ENSG00000172037

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
NEPHROTIC SYNDROME, TYPE 5, WITH OR WITHOUT OCULAR ABNORMALITIES 
PIERSON SYNDROME 

Cytogenetic Location (from UniGene)

Cytogenetic Location:3p21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 49158547 - 49162214

 Exon Info From UCSC:
NM_002292

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100069078Full LengthBC172384laminin, beta 2 (laminin S)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002283  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_002292 NP_002283 P55268 EGF
Laminin_EGF
Laminin_N
EGF_2

Related Sequences

 
mRNAGenPeptSwissProt
S77512 AAB34682 P55268
BC172384 AAI72384  
AK094050 BAC04272 Q8N9Q8
X72760 CAA51288 Q15483
X79683 CAA56130 P55268

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens LAMB2 NP_002283 R.norvegicus Lamb2 25473   NP_037106 88
M.musculus Lamb2 16779 Gene Info NP_032509 88
C.elegans lam-1 177292   NP_500734 49
A.gambiae AgaP_AGAP001381 1281797   XP_321757 42
D.melanogaster LanB1 34068   NP_476618 42

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)