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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. ACVR1B, Activin A receptor, type IB
Sequence ID:NM_020328
NM_004302
NM_020327
RefSeqGene ID:NG_022926
Entrez Gene ID:91
Ensembl ID:ENSG00000135503

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:12q13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 52345484 - 52388001

 Exon Info From UCSC:
NM_020328
NM_004302
NM_020327

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3352720Full LengthBC000254activin A receptor, type IB
5260767Full LengthBC040531activin A receptor, type IB

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_064732  NP_004293  NP_064733  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_004302 NP_004293 P36896 EC 2.7.11.30 Pkinase
Activin_recp
TGF_beta_GS
NM_020327 NP_064732     Pkinase
Activin_recp
Pkinase_Tyr
TGF_beta_GS
NM_020328 NP_064733     Pkinase
Activin_recp
Pkinase_Tyr
TGF_beta_GS

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U14722 AAA50246 P36896 EC 2.7.11.30
L10125 AAA60555 P36896 EC 2.7.11.30
L10126 AAA60556 P36896 EC 2.7.11.30
BC000254 AAH00254 P36896 EC 2.7.11.30
BC040531 AAH40531 P36896 EC 2.7.11.30
BT007072 AAP35735 P36896 EC 2.7.11.30
EU832079 ACE86741    
EU831986 ACE87427    
AK299120 BAH12954 P36896 EC 2.7.11.30
AK299496 BAH13051 P36896 EC 2.7.11.30
Z22536 CAA80258 P36896 EC 2.7.11.30

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ACVR1B NP_004293 R.norvegicus Acvr1b 29381   NP_954700 99
M.musculus Acvr1b 11479 Gene Info NP_031421 98

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)