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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. CYP17A1, Cytochrome P450, family 17, subfamily A, polypeptide 1
Sequence ID:NM_000102
RefSeqGene ID:NG_007955
Entrez Gene ID:1586
Ensembl ID:ENSG00000148795

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
17,20-LYASEDEFICIENCY, ISOLATED 

Cytogenetic Location (from UniGene)

Cytogenetic Location:10q24.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 104590291 - 104597170

NM_000102 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
28480104590289104590741
481584104591264104591367
585754104592267104592436
755970104592749104592964
9711057104593792104593878
10581287104594541104594770
12881426104595010104595148
14271895104596821104597289

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5170736Full LengthBC063388cytochrome P450, family 17, subfamily A, polypeptide 1
5171626Full LengthBC062997cytochrome P450, family 17, subfamily A, polypeptide 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000093  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000102 NP_000093 P05093 EC 1.14.99.9 p450

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M14564 AAA52151 P05093 EC 1.14.99.9
BC062997 AAH62997 P05093 EC 1.14.99.9
BC063388 AAH63388 P05093 EC 1.14.99.9
BT020000 AAV38803 P05093 EC 1.14.99.9
AK289898 BAF82587 Q1HB44  
AK312235 BAG35168 B2R5M1  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CYP17A1 NP_000093 R.norvegicus Cyp17a1 25146   NP_036885 68
M.musculus Cyp17a1 13074 Gene Info NP_031835 67
A.thaliana CYP706A2 828367   NP_194002 29
A.thaliana CYP706A3 834490   NP_199275 29
A.thaliana CYP706A5 826840   NP_192968 29
A.thaliana CYP706A1 828365   NP_567665 29
A.thaliana CYP706A4 826839   NP_192967 29
A.thaliana CYP706A6 826841   NP_192969 28
A.thaliana CYP706A7 826842   NP_192970 27

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)