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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. SMO, smoothened, frizzled family receptor
Sequence ID:NM_005631
RefSeqGene ID:NG_023340
Entrez Gene ID:6608
Ensembl ID:ENSG00000128602

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:7q32.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 128828992 - 128853385

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4127774Full LengthBC009989smoothened homolog (Drosophila)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005622  

Protein Infomation

NM_005631 NP_005622 Q99835 Fz

Related Sequences

U84401 AAB41788 Q99835
AF071494 AAC24863 Q99835
AF130867 AAD28625 Q9Y2Y5
AF120103 AAF31757 Q99835
BC009989 AAH09989 Q99835
DQ896647 ABM87646  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens SMO NP_005622 M.musculus Smo 319757 Gene Info NP_795970 94
R.norvegicus Smo 25273   NP_036939 94
A.gambiae GPRSMO 1275473   XP_314720 45
D.melanogaster smo 33196   NP_523443 45

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta