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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. XBP1, X-box binding protein 1
Sequence ID:NM_005080
NM_001079539
RefSeqGene ID:NG_012266
Entrez Gene ID:7494
Ensembl ID:ENSG00000100219

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
MAJOR AFFECTIVE DISORDERSLC6A3
MAJOR AFFECTIVE DISORDER-7 

Cytogenetic Location (from UniGene)

Cytogenetic Location:22q12.1|22q12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:22: 29190556 - 29196517

 Exon Info From UCSC:
NM_005080
NM_001079539

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3449394Full LengthBC000938X-box binding protein 1
3856898Full LengthBC012841X-box binding protein 1
3911945IncompleteBC015709X-box binding protein 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005071  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001079539 NP_001073007    
NM_005080 NP_005071 P17861 bZIP_2

Related Sequences

 
mRNAGenPeptSwissProt
M31627 AAA36031 P17861
BC000938 AAH00938 P17861
BC012841 AAH12841 P17861
BC015709 AAH15709 P17861
DQ890989 ABM81915  
DQ894165 ABM85091  
AB076383 BAB82981 P17861
AB076384 BAB82982 P17861
AK292188 BAF84877 A8K823
CR456611 CAG30497 P17861
CU013207 CAK54638  
CU013495 CAK54937  
AM393640 CAL38516  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens XBP1 NP_005071 R.norvegicus Xbp1 289754   NP_001004210 85
M.musculus Xbp1 22433 Gene Info NP_038870 83

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)