Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PPA1, pyrophosphatase (inorganic) 1
Sequence ID:NM_021129
Entrez Gene ID:5464
Ensembl ID:ENSG00000180817

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:10q11.1-q24Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 71962585 - 71993113

 Exon Info From UCSC:
NM_021129

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3345496Full LengthBC001022pyrophosphatase (inorganic) 1
6495107Full LengthBC107882pyrophosphatase (inorganic) 1
6526628Full LengthBC061581pyrophosphatase (inorganic) 1
8144037Full LengthBC105034pyrophosphatase (inorganic) 1
8144039Full LengthBC105036pyrophosphatase (inorganic) 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_066952  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_021129 NP_066952 Q15181 EC 3.6.1.1 Pyrophosphatase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF108211 AAD24964 Q15181 EC 3.6.1.1
AF154065 AAD34643 Q15181 EC 3.6.1.1
AF119665 AAF17222 Q15181 EC 3.6.1.1
AF217186 AAG36780 Q15181 EC 3.6.1.1
BC001022 AAH01022 Q15181 EC 3.6.1.1
BC061581 AAH61581 Q15181 EC 3.6.1.1
BC105034 AAI05035 Q15181 EC 3.6.1.1
BC105036 AAI05037 Q15181 EC 3.6.1.1
BC107882 AAI07883 Q15181 EC 3.6.1.1
AF092439 AAP97214 Q15181 EC 3.6.1.1
DQ893597 ABM84523    
AB026723 BAA84702 Q15181 EC 3.6.1.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PPA1 NP_066952 M.musculus Ppa1 67895 Gene Info NP_080714 94
R.norvegicus Ppa1 294504   NP_001094304 92
A.thaliana PPa6 830824   NP_196527 51

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)