Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PSMC2, proteasome (prosome, macropain) 26S subunit, ATPase, 2
Sequence ID:NM_001204453
NM_002803
Entrez Gene ID:5701
Ensembl ID:ENSG00000161057

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:7q22.1-q22.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 102988110 - 103009196


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3161790Full LengthBC002589proteasome (prosome, macropain) 26S subunit, ATPase, 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002794  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001204453 NP_001191382    
NM_002803 NP_002794 P35998 AAA

Related Sequences

 
mRNAGenPeptSwissProt
BC002589 AAH02589 P35998
EU446703 ABZ92232  
D11094 BAA01868 P35998
AB075520 BAE45763 P35998
AK298529 BAH12807 B7Z571
AK298821 BAH12878 B7Z5E2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PSMC2 NP_002794 M.musculus Psmc2 19181 Gene Info NP_035318 100
R.norvegicus Psmc2 25581   NP_150239 100
A.gambiae AgaP_AGAP011174 1270756   XP_309476 92
D.melanogaster Rpt1 35701   NP_477473 92
C.elegans rpt-1 179641   NP_506005 86
A.thaliana RPT1A 841812   NP_175778 80
S.cerevisiae RPT1 853712   NP_012777 77
N.crassa NCU02840 3880279   XP_964130 76
P.falciparum PF13_0063 814041   XP_001349843 75
S.pombe rpt1 2539862   NP_596805 75

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)