Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CLOCK, clock circadian regulator
Sequence ID:NM_001267843
NM_004898
Entrez Gene ID:9575
Ensembl ID:ENSG00000134852

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:4q12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 56298659 - 56376194


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5272026Full LengthBC041878clock homolog (mouse)
8991873Full LengthBC126157clock homolog (mouse)
8991875Full LengthBC126159clock homolog (mouse)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004889  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001267843 NP_001254772      
NM_004898 NP_004889 O15516 EC 2.3.1.48 HLH
PAS
PAS_3

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF011568 AAB83969 O15516 EC 2.3.1.48
BC041878 AAH41878 Q3ZCT4  
BC126157 AAI26158 O15516 EC 2.3.1.48
BC126159 AAI26160 O15516 EC 2.3.1.48
EU446690 ABZ92219    
HQ258670 ADR83421    
AB002332 BAA20792 O15516 EC 2.3.1.48
AB005535 BAA21774 O15516 EC 2.3.1.48
AK223549 BAD97269 Q53EU0  
AK291708 BAF84397 O15516 EC 2.3.1.48

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CLOCK NP_004889 M.musculus Clock 12753 Gene Info NP_031741 97
R.norvegicus Clock 60447   NP_068628 96
A.gambiae AgaP_AGAP005711 1276380   XP_315720 41
D.melanogaster Clk 38872   NP_001014576 39

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta