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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. ITGAV, integrin, alpha V
Sequence ID:NM_001144999
Entrez Gene ID:3685
Ensembl ID:ENSG00000138448

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, skin, soft tissue, stem cell, stomach, synovium, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q31-q32Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 187454806 - 187545624

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
8991947Full LengthBC126231integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
9020431Full LengthBC136442integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
9052620Full LengthBC144100integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
5294976IncompleteBC047454integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002201  

Protein Infomation

NM_001144999 NP_001138471    
NM_001145000 NP_001138472    
NM_002210 NP_002201 P06756 Integrin_alpha

Related Sequences

M14648 AAA36808 P06756
BC126231 AAI26232 P06756
BC136442 AAI36443 P06756
BC144100 AAI44101 B7ZLX0
EF560727 ABQ59037 A5YM53
AB209894 BAD93131 P06756
AK302550 BAG63819 B4DYQ7
AK302990 BAH13869 B7Z883

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens ITGAV NP_002201 M.musculus Itgav 16410 Gene Info NP_032428 93
R.norvegicus Itgav 296456   NP_001100019 93
A.gambiae AgaP_AGAP000032 1272247   XP_311131 36
D.melanogaster if 32661   NP_001162777 34

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta