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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CLCN2, chloride channel, voltage-sensitive 2
Sequence ID:NM_001171087
NM_001171088
NM_001171089
NM_004366
RefSeqGene ID:NG_016422
Entrez Gene ID:1181
Ensembl ID:ENSG00000114859

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
EPILEPSY, IDIOPATHIC GENERALIZEDCACNB4
EPILEPSY, IDIOPATHIC GENERALIZED, 1 
EPILEPSY, JUVENILE ABSENCEEFHC1
MYOCLONIC EPILEPSY, JUVENILECACNB4
EFHC1
GABRA1

Cytogenetic Location (from UniGene)

Cytogenetic Location:3q27-q28Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 184064393 - 184079267

 Exon Info From UCSC:
NM_001171087
NM_001171088
NM_001171089
NM_004366

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6424015Full LengthBC072004chloride channel 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004357  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001171087 NP_001164558    
NM_001171088 NP_001164559    
NM_001171089 NP_001164560    
NM_004366 NP_004357 P51788 CBS
Voltage_CLC

Related Sequences

 
mRNAGenPeptSwissProt
AF026004 AAB88807 P51788
BC021578 AAH21578 P51788
BC072004 AAH72004 P51788
AK298952 BAG61051 B4DQT9
AK302389 BAG63705 B4DYE3
AK302759 BAG63970 B4DZ58

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CLCN2 NP_004357 R.norvegicus Clcn2 29232   NP_058833 94
M.musculus Clcn2 12724 Gene Info NP_034030 94
A.gambiae GPRMGL4 1273077   XP_312021 53
D.melanogaster ClC-a 41428   NP_001097752 52
C.elegans clh-3 174187   NP_001022060 47
C.elegans clh-4 180687   NP_001024886 40

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)