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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. MLH3, mutL homolog 3 (E. coli)
Sequence ID:NM_001040108
NM_014381
RefSeqGene ID:NG_008649
Entrez Gene ID:27030
Ensembl ID:ENSG00000119684

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
COLON CANCERAKT1
APC
APC
AURKA
AXIN2
BCL10
BUB1B
CCND1
EP300
FGFR3
FLCN
NRAS
ODC1
PDGFRL
PIK3CA
PIK3CA
PLA2G2A
PTPRJ
SMAD7
TLR2
TLR4
TP53
TP53
COLON CANCER, HEREDITARYNONPOLYPOSIS, TYPE 7 
ENDOMETRIAL CANCERCDH1
MSH6
PTEN

Cytogenetic Location (from UniGene)

Cytogenetic Location:14q24.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:14: 75483784 - 75516358

 Exon Info From UCSC:
NM_001040108
NM_014381

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
8327635Full LengthBC112167mutL homolog 3 (E. coli)
5198926IncompleteBC036866mutL homolog 3 (E. coli)

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001040108 NP_001035197 Q9UHC1  
NM_014381 NP_055196    

Related Sequences

 
mRNAGenPeptSwissProt
L40399 AAC42005 Q9UHC1
AF195657 AAF23904 Q9UHC1
BC036866 AAH36866 Q6PIC9
BC112167 AAI12168 Q2M1Z1
HQ258639 ADR83390  
AB039667 BAA92353 Q9UHC1
AK298777 BAH12867 B7Z5D1
AL833875 CAD38732 Q8N3N3

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MLH3 NP_001035197 M.musculus Mlh3 217716 Gene Info NP_780546 73
R.norvegicus Mlh3 314320   NP_001101513 72

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)