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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. CD74, CD74 molecule, major histocompatibility complex, class II invariant chain
Sequence ID:NM_001025158
RefSeqGene ID:NG_029730
Entrez Gene ID:972
Ensembl ID:ENSG00000019582

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:5q32Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 149781203 - 149792314

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4763768Full LengthBC024272CD74 molecule, major histocompatibility complex, class II invariant chain
4853578Full LengthBC018726CD74 molecule, major histocompatibility complex, class II invariant chain

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001020330  

Protein Infomation

NM_001025158 NP_001020329    
NM_001025159 NP_001020330 P04233 Thyroglobulin_1
NM_004355 NP_004346    

Related Sequences

M28590 AAA35996 O78208
K01144 AAA36304 P04233
M28588 AAA58655 O19685
BC018726 AAH18726 P04233
BC024272 AAH24272 P04233
M28589 AAO49820  
BT019505 AAV38312 P04233
DQ892005 ABM82931  
DQ895194 ABM86120  
AK292076 BAF84765 P04233
AK297889 BAG60210 P04233
AK300669 BAG62354 B4DUJ2
X00497 CAA25192 P04233
X00497 CAA25193 P04233

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens CD74 NP_001020330 M.musculus Cd74 16149 Gene Info NP_001036070 77
R.norvegicus Cd74 25599   NP_037201 76

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta