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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. TWF2, twinfilin, actin-binding protein, homolog 2 (Drosophila)
Sequence ID:NM_007284
Entrez Gene ID:11344
Ensembl ID:ENSG00000247596

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:3p21.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 52262627 - 52273084

NM_007284 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
366265226262652263216
6277485226367652263797
7498995226393552264085
90010255226488552265010
102611305226514252265246
113112265226545952265554
122714055226595952266137
140614835226904452269121
148416595227300752273182

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2822004Full LengthBC000327twinfilin, actin-binding protein, homolog 2 (Drosophila)
2957960Full LengthBC003161twinfilin, actin-binding protein, homolog 2 (Drosophila)
3452300Full LengthBC016452twinfilin, actin-binding protein, homolog 2 (Drosophila)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_009215  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_007284 NP_009215 Q6IBS0 Cofilin_ADF

Related Sequences

 
mRNAGenPeptSwissProt
BC000327 AAH00327 Q6IBS0
BC003161 AAH03161 Q6IBS0
BC016452 AAH16452 Q6IBS0
AF109365 AAQ13513 Q6IBS0
DQ891754 ABM82680  
DQ894936 ABM85862  
Y17169 CAB38055 Q6IBS0
AL136773 CAB66707 Q6IBS0
CR456732 CAG33013 Q6IBS0
CR533520 CAG38551 Q6IBS0

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens TWF2 NP_009215 M.musculus Twf2 23999 Gene Info NP_036006 97
N.crassa NCU07512 3874131   XP_957984 32
S.pombe twf1 2539064   NP_588449 27

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)