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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. IDH3B, isocitrate dehydrogenase 3 (NAD+) beta
Sequence ID:NM_001258384
RefSeqGene ID:NG_012149
Entrez Gene ID:3420
Ensembl ID:ENSG00000101365

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:20p13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:20: 2641111 - 2644855

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3536921Full LengthBC001960isocitrate dehydrogenase 3 (NAD+) beta

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_008830  NP_777280  

Protein Infomation

NM_001258384 NP_001245313      
NM_006899 NP_008830 O43837 EC Iso_dh
NM_174855 NP_777280     Iso_dh

Related Sequences

BC001960 AAH01960 O43837 EC
DQ892561 ABM83487    
DQ895776 ABM86702    
DQ895816 ABM86742    
EU832019 ACE86681    
EU831924 ACE87365    
AK001905 BAA91971 O43837 EC
AK315641 BAG38008 O43837 EC
AK300485 BAG62200 B4DU38  
AL050094 CAB43266 O43837 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens IDH3B NP_008830 M.musculus Idh3b 170718 Gene Info NP_570954 94
R.norvegicus Idh3B 94173   NP_446033 94
A.gambiae AgaP_AGAP007786 1278179   XP_317729 62
C.elegans C37E2.1 181528   NP_510362 62
D.melanogaster CG6439 42586   NP_001163682 61
A.thaliana IDH2 816218   NP_179304 53
A.thaliana IDH1 829679   NP_195252 52
N.crassa NCU00775 3881080   XP_964931 51
S.pombe idh1 2541894   NP_594397 49
S.cerevisiae IDH1 855691   NP_014361 46

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)