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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MYOC, myocilin, trabecular meshwork inducible glucocorticoid response
Sequence ID:NM_000261
RefSeqGene ID:NG_008859
Entrez Gene ID:4653
Ensembl ID:ENSG00000034971

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
GLAUCOMA 1A, PRIMARY OPEN ANGLECYP1B1
LMX1B

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q23-q24Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 171604556 - 171621773

NM_000261 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
191309171604558171605848
13101435171607736171607861
14362061171621147171621772

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5179076Full LengthBC029261myocilin, trabecular meshwork inducible glucocorticoid response

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000252  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000261 NP_000252 Q99972 OLF

Related Sequences

 
mRNAGenPeptSwissProt
AF001620 AAC51725 Q99972
U85257 AAC52051 Q99972
BC029261 AAH29261 Q99972
DQ892415 ABM83341  
DQ895629 ABM86555  
FJ227302 ACI42983 B6ECI7
FJ237046 ACI62292 B6V6K6
FJ237047 ACI62293 B6V6K7
D88214 BAA23531 Q99972
AK097310 BAC04997 Q8N854
AK315443 BAG37831 Q99972
AK300924 BAG62556 B4DV44
AK300943 BAG62572 B4DV60
AK301297 BAG62854 B4DVZ2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MYOC NP_000252 M.musculus Myoc 17926 Gene Info NP_034995 82
R.norvegicus Myoc 81523   NP_110492 82

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)