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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. IREB2, iron-responsive element binding protein 2
Sequence ID:NM_004136
Entrez Gene ID:3658
Ensembl ID:ENSG00000136381

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, placenta, pooled tissue, prostate, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:15q25.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:15: 78730583 - 78792880

 Exon Info From UCSC:
NM_004136

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40126032Full LengthBC117481iron-responsive element binding protein 2
40126034Full LengthBC117483iron-responsive element binding protein 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004127  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_004136 NP_004127   Aconitase
Aconitase_C

Related Sequences

 
mRNAGenPeptSwissProt
M58511 AAA69901 P48200
U20180 AAA79926 P48200
BC017880 AAH17880 Q8WVK6
BC117481 AAI17482 P48200
BC117483 AAI17484 P48200
HQ258663 ADR83414  
AB209403 BAD92640 P48200
AK292992 BAF85681 P48200
AL133439 CAB62825 P48200

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens IREB2 NP_004127 M.musculus Ireb2 64602 Gene Info NP_073146 94
R.norvegicus Ireb2 64831   NP_074054 94

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)