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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. ERCC1, excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
Sequence ID:NM_001166049
NM_001983
NM_202001
RefSeqGene ID:NG_015839
Entrez Gene ID:2067
Ensembl ID:ENSG00000012061

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, t-cell, testis, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
CEREBROOCULOFACIOSKELETAL SYNDROME 4 

Cytogenetic Location (from UniGene)

Cytogenetic Location:19q13.32Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 45912871 - 45927097

 Exon Info From UCSC:
NM_001166049
NM_001983
NM_202001

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2824122Full LengthBC008930excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
6526165Full LengthBC052813excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001974  NP_973730  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001166049 NP_001159521    
NM_001983 NP_001974 P07992 HHH
Rad10
NM_202001 NP_973730   HHH
Rad10

Related Sequences

 
mRNAGenPeptSwissProt
M28650 AAA35810 P07992
M13194 AAA52394 P07992
AF001925 AAC16253 P07992
BC008930 AAH08930 P07992
BC052813 AAH52813 P07992
AF433652 AAL56574 Q8WWH8
BT019806 AAV38609 P07992
DQ893002 ABM83928  
DQ896248 ABM87247  
AB069681 BAB62810 P07992
AK314884 BAG37398 B2RC01
AK092039 BAG52472 B3KRR0

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ERCC1 NP_001974 M.musculus Ercc1 13870 Gene Info NP_031974 86
R.norvegicus Ercc1 292673   NP_001099698 84
S.pombe swi10 2540887   NP_596115 52
A.gambiae AgaP_AGAP004029 1278845   XP_318485 48
A.thaliana ERCC1 819685   NP_187172 47
D.melanogaster Ercc1 36654   NP_477468 47
N.crassa NCU07066 3876480   XP_960331 46

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)