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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. SPTLC2, serine palmitoyltransferase, long chain base subunit 2
Sequence ID:NM_004863
RefSeqGene ID:NG_028282
Entrez Gene ID:9517
Ensembl ID:ENSG00000100596

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, placenta, pooled tissue, prostate, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:14q24.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:14: 77973691 - 78083110

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3688136Full LengthBC005123serine palmitoyltransferase, long chain base subunit 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004854  

Protein Infomation

NM_004863 NP_004854 O15270 EC Aminotran_1_2

Related Sequences

U15555 AAC50871 O15270 EC
BC005123 AAH05123 O15270 EC
DQ893297 ABM84223    
DQ896786 ABM87785    
AB011098 BAA25452 O15270 EC
Y08686 CAA69942 O15270 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens SPTLC2 NP_004854 M.musculus Sptlc2 20773 Gene Info NP_035609 96
R.norvegicus Sptlc2 366697   NP_001032174 96
A.gambiae AgaP_AGAP007941 1278014   XP_317536 58
D.melanogaster lace 34910   NP_476614 58
C.elegans sptl-2 266646   NP_505064 55
N.crassa NCU00447 3872913   XP_956766 51
S.pombe lcb2 3361415   NP_001018279 50
S.cerevisiae LCB2 851634   NP_010347 48

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)