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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. TH, Tyrosine hydroxylase
Sequence ID:NM_199292
NM_199293
NM_000360
RefSeqGene ID:NG_008128
Entrez Gene ID:7054
Ensembl ID:ENSG00000180176

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssemblies

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
SEGAWA SYNDROME, RECESSIVE 

Cytogenetic Location (from UniGene)

Cytogenetic Location:11p15.5Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 2186908 - 2189336

 Exon Info From UCSC:
NM_199292
NM_199293
NM_000360

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
8143970Full LengthBC104967tyrosine hydroxylase
9052124Full LengthBC143611tyrosine hydroxylase
9052127Full LengthBC143614tyrosine hydroxylase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000351  NP_954987  NP_954986  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000360 NP_000351     Biopterin_H
NM_199292 NP_954986 P07101 EC 1.14.16.2 Biopterin_H
NM_199293 NP_954987     Biopterin_H

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M20911 AAA61167 P07101 EC 1.14.16.2
M20912 AAA61168 Q7KZ44  
M24790 AAA61174 P78428  
M17589 AAA61179 P07101 EC 1.14.16.2
BC104967 AAI04968 Q2M3B4  
BC143611 AAI43612 P07101 EC 1.14.16.2
BC143614 AAI43615 B7ZL73  
AY144494 AAN39538 Q8IZE2  
AY144495 AAN39539 Q8IZE1  
DQ677336 ABG73364 Q0PWM3  
DQ677337 ABG73365 Q0PWM2  
X05290 CAA28908 P07101 EC 1.14.16.2
Y00414 CAA68472 P07101 EC 1.14.16.2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens TH NP_954986 R.norvegicus Th 25085   NP_036872 89
M.musculus Th 21823 Gene Info NP_033403 88
C.elegans cat-2 173411   NP_871903 54
A.gambiae AgaP_AGAP006023 1276690   XP_316061 52
D.melanogaster ple 38746   NP_476897 52

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)