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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PPP3CA, protein phosphatase 3, catalytic subunit, alpha isozyme
Sequence ID:NM_000944
Entrez Gene ID:5530
Ensembl ID:ENSG00000138814

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:4q24Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 101947023 - 102267953

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5227691Full LengthBC025714protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000935  

Protein Infomation

NM_000944 NP_000935 Q08209 EC Metallophos
NM_001130691 NP_001124163      
NM_001130692 NP_001124164      

Related Sequences

L14778 AAA02631 Q08209 EC
J05480 AAA35634 Q9UMM5  
BC025714 AAH25714 Q08209 EC
AY904364 AAY17314 A1A441  
EU192652 ABW74484 Q08209 EC
EU192653 ABW74485 A8W6Z8  
AK290532 BAF83221 Q08209 EC
AB451338 BAG70152 Q08209 EC
AB451487 BAG70301 Q08209 EC
AL353950 CAB89253 Q08209 EC
AM393486 CAL38363    
AM393713 CAL38589    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens PPP3CA NP_000935 M.musculus Ppp3ca 19055 Gene Info NP_032939 100
R.norvegicus Ppp3ca 24674   NP_058737 100
A.gambiae AgaP_AGAP001279 1281899   XP_321872 87
D.melanogaster Pp2B-14D 32624   NP_523373 83
D.melanogaster CanA-14F 8674098   NP_727985 80
C.elegans tax-6 177943   NP_001021293 78
N.crassa NCU03804 3877353   XP_961193 68
S.pombe ppb1 2540024   NP_596178 66
S.cerevisiae CNA1 851153   NP_013537 57

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta