Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. HMGB2, high mobility group box 2
Sequence ID:NM_001130688
NM_001130689
NM_002129
Entrez Gene ID:3148
Ensembl ID:ENSG00000164104

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:4q31Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 174253230 - 174255509

 Exon Info From UCSC:
NM_001130688
NM_001130689
NM_002129

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2963045Full LengthBC001063high-mobility group box 2
6163784Full LengthBC100019high-mobility group box 2
2900706IncompleteBC000903high-mobility group box 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002120  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001130688 NP_001124160    
NM_001130689 NP_001124161    
NM_002129 NP_002120 P26583 HMG_box

Related Sequences

 
mRNAGenPeptSwissProt
BC001063 AAH01063 P26583
BC100019 AAI00020 P26583
BT019782 AAV38585 P26583
BT019783 AAV38586 Q5U071
DQ892288 ABM83214  
DQ895487 ABM86413  
AK311864 BAG34805 P26583
X62534 CAA44395 P26583
Z17240 CAA78938 P26583

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens HMGB2 NP_001124160 R.norvegicus Hmgb2 29395   NP_058883 99
R.norvegicus RGD1564519 498072   XP_573272 99
M.musculus Hmgb2 97165 Gene Info NP_032278 97

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta