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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PPIB, Peptidylprolyl isomerase B (cyclophilin B)
Sequence ID:NM_000942
RefSeqGene ID:NG_012979
Entrez Gene ID:5479
Ensembl ID:ENSG00000166794

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:15q21-q22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:15: 64448014 - 64455218

NM_000942 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
193486444801464448343
3495336444892364449107
5346276445230264452395
6287416445423964454352
74210456445505064455353

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2966791Full LengthBC001125peptidylprolyl isomerase B (cyclophilin B)
3502055Full LengthBC008848peptidylprolyl isomerase B (cyclophilin B)
4248828Full LengthBC020800peptidylprolyl isomerase B (cyclophilin B)
4896656Full LengthBC032138peptidylprolyl isomerase B (cyclophilin B)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000933  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000942 NP_000933 P23284 EC 5.2.1.8 Pro_isomerase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M60457 AAA35733 P23284 EC 5.2.1.8
M63573 AAA36601 P23284 EC 5.2.1.8
M60857 AAA52150 P23284 EC 5.2.1.8
BC001125 AAH01125 P23284 EC 5.2.1.8
BC008848 AAH08848 P23284 EC 5.2.1.8
BC020800 AAH20800 P23284 EC 5.2.1.8
BC032138 AAH32138 P23284 EC 5.2.1.8
DQ892289 ABM83215    
DQ895488 ABM86414    
D28465 BAA05831    
AK291149 BAF83838 P23284 EC 5.2.1.8
CR456829 CAG33110 P23284 EC 5.2.1.8

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PPIB NP_000933 M.musculus Ppib 19035 Gene Info NP_035279 94
R.norvegicus Ppib 64367   NP_071981 93
A.gambiae AgaP_AGAP007088 1270014   XP_308669 71
N.crassa NCU01200 5847555   XP_001728305 69
C.elegans cyn-5 173374   NP_493624 68
D.melanogaster CG2852 37591   NP_611695 68
S.pombe cyp4 2541395   NP_596532 68
C.elegans cyn-6 175231   NP_497257 67
A.thaliana ROC7 835985   NP_200679 64
A.thaliana CYP5 817546   NP_180557 62
S.cerevisiae CPR5 851898   NP_010590 56
P.falciparum CyP22 810711   XP_001347835 53

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)