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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CHRNA1, cholinergic receptor, nicotinic, alpha 1 (muscle)
Sequence ID:NM_000079
NM_001039523
RefSeqGene ID:NG_008172
Entrez Gene ID:1134
Ensembl ID:ENSG00000138435

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
MULTIPLE PTERYGIUM SYNDROME, LETHAL TYPECHRND
CHRNG
MYASTHENIC SYNDROME, FAST-CHANNEL CONGENITALCHRND
CHRNE
MYASTHENIC SYNDROME, SLOW-CHANNEL CONGENITALCHRNB1
CHRND
CHRNE

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q31.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 175612720 - 175629141

 Exon Info From UCSC:
NM_000079
NM_001039523

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000070  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000079 NP_000070 Q53SH4 Neur_chan_LBD
Neur_chan_memb
NM_001039523 NP_001034612 P02708  

Related Sequences

 
mRNAGenPeptSwissProt
S77094 AAD14247 P02708
DQ323657 ABD27888 A9X443
DQ323658 ABD27889 A9X444
AK291338 BAF84027 Q53SH4
AK315312 BAG37716 Q53SH4
AK299445 BAG61418 P02708
Y00762 CAA68731 Q53SH4
P02708

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CHRNA1 NP_001034612 M.musculus Chrna1 11435 Gene Info NP_031415 94
R.norvegicus Chrna1 79557   NP_077811 94

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta