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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PLEC, plectin
Sequence ID:NM_000445
NM_201378
NM_201379
NM_201380
NM_201381
NM_201382
NM_201383
NM_201384
RefSeqGene ID:NG_012492
Entrez Gene ID:5339
Ensembl ID:ENSG00000178209

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebrum, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
EPIDERMOLYSIS BULLOSA SIMPLEX WITH PYLORIC ATRESIA 
EPIDERMOLYSIS BULLOSA SIMPLEX, OGNA TYPE 
MUSCULAR DYSTROPHY WITH EPIDERMOLYSIS BULLOSA SIMPLEX 
MUSCULAR DYSTROPHY, LIMB-GIRDLE,TYPE 2Q 

Cytogenetic Location (from UniGene)

Cytogenetic Location:8q24Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 145013517 - 145013629

 Exon Info From UCSC:
NM_000445
NM_201378
NM_201379
NM_201380
NM_201381
NM_201382
NM_201383
NM_201384

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3346810IncompleteBC007597plectin 1, intermediate filament binding protein 500kDa

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_958783  NP_958784  NP_958781  NP_000436  NP_958786  NP_958785  NP_958782  NP_958780  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000445 NP_000436   CH
Plectin
NM_201378 NP_958780   CH
Plectin
NM_201379 NP_958781   CH
Plectin
NM_201380 NP_958782 Q15149 CH
Plectin
S10_plectin
NM_201381 NP_958783   CH
Plectin
NM_201382 NP_958784   CH
Plectin
NM_201383 NP_958785   CH
Plectin
NM_201384 NP_958786   CH
Plectin

Related Sequences

 
mRNAGenPeptSwissProt
U53204 AAB05427 Q15149
BC007597 AAH07597 Q96IE3
AF330792 AAL37483 Q8WXV5
AY480044 AAR95677 Q15149
AY480045 AAR95678 Q15149
AY480046 AAR95679 Q15149
AY480047 AAR95680 Q15149
AY480048 AAR95681 Q15149
AY480049 AAR95682 Q15149
AY480050 AAR95683 Q15149
AY480051 AAR95684 Q15149
X97053 CAA65765 Q15149

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PLEC NP_958782 M.musculus Plec 18810 Gene Info NP_001157012 94
R.norvegicus Plec 64204   NP_071796 94

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)