Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. HMGB1, high mobility group box 1
Sequence ID:NM_002128
Entrez Gene ID:3146
Ensembl ID:ENSG00000189403

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:13q12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:13: 31035105 - 31039985

NM_002128 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2901382Full LengthBC003378high-mobility group box 1
4041682Full LengthBC030981high-mobility group box 1
4818524Full LengthBC067732high-mobility group box 1
5268698Full LengthBC066889high-mobility group box 1
8860319Full LengthBC141844high-mobility group box 1
100000676BC140013high-mobility group box 1
100013567BC140018high-mobility group box 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002119  

Protein Infomation

NM_002128 NP_002119 P09429 HMG_box

Related Sequences

BC003378 AAH03378 P09429
BC030981 AAH30981 P09429
BC066889 AAH66889 P09429
BC067732 AAH67732 P09429
BC140013 AAI40014  
BC140018 AAI40019  
BC141844 AAI41845 P09429
BT006940 AAP35586 P09429
AY377859 AAQ91389 P09429
BT020159 AAV38961 P09429
D63874 BAA09924 P09429
AB208998 BAD92235 Q59GW1
AK291494 BAF84183 P09429
AK057120 BAG51867 B3KQ05
AK122825 BAG53745 P09429
AK304506 BAH14201 B7Z965
X12597 CAA31110 P09429
CR456863 CAG33144 P09429
CR749614 CAH18408 P09429

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens HMGB1 NP_002119 M.musculus Hmgb1 15289 Gene Info NP_034569 99
R.norvegicus LOC689398 689398   XP_001068941 97
R.norvegicus LOC690940 690940   XP_001076232 97
A.gambiae AgaP_AGAP000005 1272270   XP_311155 49
D.melanogaster Dsp1 117294   NP_996485 47
C.elegans hmg-1.2 175890   NP_498375 45

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta