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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. GPX4, glutathione peroxidase 4
Sequence ID:NM_001039847
Entrez Gene ID:2879
Ensembl ID:ENSG00000167468

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:19p13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 1104005 - 1106778

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3945177Full LengthBC011836glutathione peroxidase 4 (phospholipid hydroperoxidase)
4581069Full LengthBC021567glutathione peroxidase 4 (phospholipid hydroperoxidase)
4821595Full LengthBC022071glutathione peroxidase 4 (phospholipid hydroperoxidase)
5227887Full LengthBC032695glutathione peroxidase 4 (phospholipid hydroperoxidase)
5742889Full LengthBC046163glutathione peroxidase 4 (phospholipid hydroperoxidase)
5744771Full LengthBC039849glutathione peroxidase 4 (phospholipid hydroperoxidase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002076  

Protein Infomation

NM_001039847 NP_001034936      
NM_001039848 NP_001034937      
NM_002085 NP_002076 P36969 EC GSHPx

Related Sequences

BC010157 AAH10157 Q6PJX4  
BC011836 AAH11836 P36969 EC
BC021567 AAH21567 P36969 EC
BC022071 AAH22071 P36969 EC
BC032695 AAH32695 P36969 EC
BC039849 AAH39849 P36969 EC
BC046163 AAH46163 Q6PI42  
X71973 CAA50793 P36969 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens GPX4 NP_001034937 M.musculus Gpx4 625249 Gene Info NP_001032830 86
R.norvegicus Gpx4 29328   NP_001034938 81
A.thaliana GPX6 826765   NP_192897 52
C.elegans R05H10.5 187630   NP_497078 50
C.elegans F26E4.12 184981   NP_492598 50
A.gambiae GPXH1 1274092   XP_313167 48
N.crassa NCU09534 3874066   XP_957919 45
S.cerevisiae HYR1 854855   NP_012303 45
S.pombe gpx1 2540222   NP_596146 43
D.melanogaster PHGPx 38413   NP_728869 42

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)