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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. KRT5, keratin 5
Sequence ID:NM_000424
RefSeqGene ID:NG_008297
Entrez Gene ID:3852
Ensembl ID:ENSG00000186081

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
DOWLING-DEGOS DISEASE 
EPIDERMOLYSIS BULLOSA OF HANDS AND FEETITGB4
KRT14
EPIDERMOLYSIS BULLOSA SIMPLEX WITH MIGRATORY CIRCINATE ERYTHEMA 
EPIDERMOLYSIS BULLOSA SIMPLEX WITHMOTTLED PIGMENTATION 
EPIDERMOLYSIS BULLOSA SIMPLEX, DOWLING-MEARA TYPEKRT14
EPIDERMOLYSIS BULLOSA SIMPLEX, KOEBNER TYPEKRT14

Cytogenetic Location (from UniGene)

Cytogenetic Location:12q13.13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 52908360 - 52914178

NM_000424 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
206835290836052909023
6847185290958152909615
7199395291042052910640
94010655291089052911015
106612305291137352911537
123113265291168052911775
132713875291188652911946
138816025291272952912943
160323205291352552914242

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5428482Full LengthBC024292keratin 5
5479022Full LengthBC042132keratin 5
6106996Full LengthBC071906keratin 5

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000424 NP_000415 P13647  

Related Sequences

 
mRNAGenPeptSwissProt
M21389 AAA36143 P13647
M19723 AAA36145 P13647
BC024292 AAH24292 P13647
BC042132 AAH42132 P13647
BC071906 AAH71906 P13647
AY373434 AAQ81588 P13647
DQ892846 ABM83772  
DQ896092 ABM87091  
AK296823 BAG59394 B4DL32
AK303972 BAG64893 B4E1T1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens KRT5 NP_000415 M.musculus Krt5 110308 Gene Info NP_081287 90

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)