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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. EIF4G1, eukaryotic translation initiation factor 4 gamma, 1
Sequence ID:NM_001194946
NM_001194947
NM_004953
NM_182917
NM_198241
NM_198242
NM_198244
RefSeqGene ID:NG_016850
Entrez Gene ID:1981
Ensembl ID:ENSG00000114867

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
PARKINSON DISEASE 18 

Cytogenetic Location (from UniGene)

Cytogenetic Location:3q27-qterMitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 184033117 - 184038499

 Exon Info From UCSC:
NM_001194946
NM_001194947
NM_004953
NM_182917
NM_198241
NM_198242
NM_198244

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9021760Full LengthBC140892eukaryotic translation initiation factor 4 gamma, 1
9021764Full LengthBC140896eukaryotic translation initiation factor 4 gamma, 1
3611484IncompleteBC007788eukaryotic translation initiation factor 4 gamma, 1
6146899IncompleteBC065256eukaryotic translation initiation factor 4 gamma, 1
6580118IncompleteBC082764eukaryotic translation initiation factor 4 gamma, 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_937885  NP_937887  NP_886553  NP_937884  NP_004944  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001194946 NP_001181875    
NM_001194947 NP_001181876    
NM_004953 NP_004944   W2
MA3
MIF4G
NM_182917 NP_886553   W2
MA3
MIF4G
NM_198241 NP_937884   W2
MA3
MIF4G
NM_198242 NP_937885   W2
MA3
MIF4G
NM_198244 NP_937887   W2
MA3
MIF4G

Related Sequences

 
mRNAGenPeptSwissProt
AF002815 AAC78442 O95065
AF002816 AAC78443 Q04637
AF104913 AAC82471 Q04637
BC007788 AAH07788 Q96I65
BC140892 AAI40893 B2RU06
BC140896 AAI40897 B2RU10
AY082886 AAL92872 Q04637
AF281070 AAM69365 Q04637
BT007282 AAP35946 Q96I65
D12686 BAA02185 Q04637
AK131407 BAD18554 Q04637
AB210013 BAE06095 Q4LE58
AK294567 BAG57762 B4DGF1
AK299763 BAG61651 B4DSI9
AJ001046 CAA04500 Q04637
BX647812 CAI46013 Q04637

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens EIF4G1 NP_886553 R.norvegicus Eif4g1 287986   XP_002727969 92
M.musculus Eif4g1 208643 Gene Info NP_001005331 92
A.gambiae AgaP_AGAP002502 1273460   XP_312438 35
D.melanogaster eIF4G 43839   NP_524640 28

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta