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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. TMEM50B, Transmembrane protein 50B
Sequence ID:NM_006134
RefSeqGene ID:NG_007570
Entrez Gene ID:757
Ensembl ID:ENSG00000142188

Database Links

UniGeneEntrez GeneEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, bone, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:21q22.11Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:21: 34823009 - 34852251

NM_006134 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3342648Full LengthBC000569transmembrane protein 50B

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006125  

Protein Infomation

NM_006134 NP_006125 P56557 UPF0220

Related Sequences

AF045606 AAC05974 P56557
BC000569 AAH00569 P56557
AY358634 AAQ88997 P56557
AY820138 AAV68502 P56557
DQ286229 ABB91377 Q2V8N0
AK129657 BAC85209 Q6ZPB0
AK311870 BAG34811 P56557

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens TMEM50B NP_006125 M.musculus Tmem50b 77975 Gene Info NP_084294 99
R.norvegicus Tmem50b 360698   NP_001020185 99
C.elegans Y74C10AL.2 171806   NP_490985 52

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)