Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. TUBB4B, Tubulin, beta 4B class IVb
Sequence ID:NM_006088
Entrez Gene ID:10383
Ensembl ID:ENSG00000188229

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:9q34Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:9: 140135765 - 140137196

NM_006088 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2964559Full LengthBC004188tubulin, beta 2C
3544236Full LengthBC001911tubulin, beta 2C
3603755Full LengthBC012835tubulin, beta 2C
3614023Full LengthBC002783tubulin, beta 2C
3616531Full LengthBC024038tubulin, beta 2C
3944735Full LengthBC002885tubulin, beta 2C
4024979Full LengthBC019359tubulin, beta 2C
4127195Full LengthBC007889tubulin, beta 2C
4385885Full LengthBC039175tubulin, beta 2C
4905049Full LengthBC071889tubulin, beta 2C
5110038Full LengthBC019829tubulin, beta 2C
5274343Full LengthBC029529tubulin, beta 2C
3508410IncompleteBC008006tubulin, beta 2C

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006079  

Protein Infomation

NM_006088 NP_006079 P68371 Tubulin

Related Sequences

BC001911 AAH01911 P68371
BC002783 AAH02783 P68371
BC002885 AAH02885 P68371
BC004188 AAH04188 P68371
BC007889 AAH07889 P68371
BC008006 AAH08006 Q96HX0
BC012835 AAH12835 P68371
BC019359 AAH19359 P68371
BC019829 AAH19829 P68371
BC024038 AAH24038 Q8IZ29
BC029529 AAH29529 Q8N6N5
BC039175 AAH39175 P68371
BC071889 AAH71889 P68371
AY167990 AAN87335 Q8IWP6
HQ447292 ADQ31779  
AK021414 BAG51031 B3KML9
AK298087 BAG60373 B4DNW1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens TUBB4B NP_006079 M.musculus Tubb4b 227613 Gene Info NP_666228 100
R.norvegicus Tubb4b 296554   NP_954525 100
A.gambiae AgaP_AGAP010929 1271023   XP_309765 97
D.melanogaster betaTub56D 37238   NP_523795 97
C.elegans tbb-4 181170   NP_509585 94
A.thaliana TUB1 843911   NP_177706 86
A.thaliana TUB5 838590   NP_564101 86
N.crassa NCU04054 3873840   XP_957669 85
S.pombe nda3 2540582   NP_596650 77
S.cerevisiae TUB2 850506   NP_116616 76

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)