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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PRKAA1, protein kinase, AMP-activated, alpha 1 catalytic subunit
Sequence ID:NM_006251
NM_206907
Entrez Gene ID:5562
Ensembl ID:ENSG00000132356

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:5p12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 40762692 - 40798287

 Exon Info From UCSC:
NM_006251
NM_206907

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4839033Full LengthBC048980protein kinase, AMP-activated, alpha 1 catalytic subunit
5265054Full LengthBC037303protein kinase, AMP-activated, alpha 1 catalytic subunit

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006242  NP_996790  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_006251 NP_006242 Q13131 EC 2.7.11.1
EC 2.7.11.31
EC 2.7.11.27
EC 2.7.11.26
Pkinase
NM_206907 NP_996790     Pkinase
Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U22456 AAA64850 Q13131 EC 2.7.11.1
EC 2.7.11.31
EC 2.7.11.27
EC 2.7.11.26
AF100763 AAD43027 Q13131 EC 2.7.11.1
EC 2.7.11.31
EC 2.7.11.27
EC 2.7.11.26
BC012622 AAH12622 Q96E92  
BC037303 AAH37303 Q13131 EC 2.7.11.1
EC 2.7.11.31
EC 2.7.11.27
EC 2.7.11.26
BC048980 AAH48980 Q13131 EC 2.7.11.1
EC 2.7.11.31
EC 2.7.11.27
EC 2.7.11.26
JF432366 ADZ15583    
AB022017 BAA36547 Q13131 EC 2.7.11.1
EC 2.7.11.31
EC 2.7.11.27
EC 2.7.11.26
AK312947 BAG35788 Q13131 EC 2.7.11.1
EC 2.7.11.31
EC 2.7.11.27
EC 2.7.11.26
Y12856 CAA73361 Q13131 EC 2.7.11.1
EC 2.7.11.31
EC 2.7.11.27
EC 2.7.11.26

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PRKAA1 NP_996790 R.norvegicus Prkaa1 65248   NP_062015 99
M.musculus Prkaa1 105787 Gene Info NP_001013385 99
A.thaliana KIN10 821259   NP_001118546 56
A.thaliana KIN11 822566   NP_566843 53

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta