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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. MARCH6, Membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
Sequence ID:NM_005885
Entrez Gene ID:10299
Ensembl ID:ENSG00000145495

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:5p15.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 10353827 - 10435491

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9020450Full LengthBC136461membrane-associated ring finger (C3HC4) 6
9020451Full LengthBC136462membrane-associated ring finger (C3HC4) 6
40148250Full LengthBC142679membrane-associated ring finger (C3HC4) 6
40148713Full LengthBC142694membrane-associated ring finger (C3HC4) 6
6018770IncompleteBC046148membrane-associated ring finger (C3HC4) 6

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005876  

Protein Infomation

NM_001270660 NP_001257589    
NM_001270661 NP_001257590    
NM_005885 NP_005876 O60337 zf-C3HC4

Related Sequences

AF009301 AAB66840 O60337
BC046148 AAH46148 O60337
BC136461 AAI36462 O60337
BC136462 AAI36463 O60337
BC142679 AAI42680 O60337
BC142694 AAI42695 O60337
AB011169 BAA25523 O60337
AK314686 BAG37238 B2RBJ1
AK000970 BAG50840 B3KM28
AK296585 BAG59204 B4DKJ2
AK299339 BAG61341 B4DRM9
AK300034 BAG61845 B4DT33

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens MARCH6 NP_005876 M.musculus March6 223455 Gene Info NP_766194 98
R.norvegicus March6 294862   XP_215517 98
A.gambiae AgaP_AGAP007204 1269927   XP_308581 59
D.melanogaster CG1317 38300   NP_001163328 54
C.elegans marc-6 172986   NP_492823 43
A.thaliana AT4G34100 829556   NP_195136 34

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)