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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. POLR2H, polymerase (RNA) II (DNA directed) polypeptide H
Sequence ID:NM_006232
Entrez Gene ID:5437
Ensembl ID:ENSG00000163882

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:3q28Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 184081220 - 184086334

NM_006232 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3504683Full LengthBC000739polymerase (RNA) II (DNA directed) polypeptide H

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006223  

Protein Infomation

NM_006232 NP_006223 P52434 RNA_pol_Rpb8

Related Sequences

U37689 AAA91458 P52434
BC000739 AAH00739 P52434
EU446997 ABZ92526  
Z49199 CAA89060 P52434

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens POLR2H NP_006223 M.musculus Polr2h 245841 Gene Info NP_663607 100
R.norvegicus Polr2h 498109   NP_001128261 100
D.melanogaster Rpb8 40415   NP_649352 79
A.gambiae AgaP_AGAP012397 1280317   XP_320161 76
C.elegans rpb-8 175660   NP_498036 64
A.thaliana NRPB8B 825129   NP_191519 50
A.thaliana NRPB8A 841866   NP_175827 50
N.crassa NCU08030 3878866   XP_962700 47
S.cerevisiae RPB8 854399   NP_014867 39

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)