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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MAP4K4, mitogen-activated protein kinase kinase kinase kinase 4
Sequence ID:NM_001242559
NM_001242560
NM_004834
NM_145686
NM_145687
Entrez Gene ID:9448
Ensembl ID:ENSG00000071054

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, skin, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q11.2-q12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 102483016 - 102507958

 Exon Info From UCSC:
NM_004834
NM_145686
NM_145687

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100062694Full LengthBC156887mitogen-activated protein kinase kinase kinase kinase 4
4279933IncompleteBC010909mitogen-activated protein kinase kinase kinase kinase 4
5302120IncompleteBC045694mitogen-activated protein kinase kinase kinase kinase 4
6046237IncompleteBC040077mitogen-activated protein kinase kinase kinase kinase 4
100062311BC156089mitogen-activated protein kinase kinase kinase kinase 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_663720  NP_663719  NP_004825  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001242559 NP_001229488 O95819 EC 2.7.11.1  
NM_001242560 NP_001229489      
NM_004834 NP_004825     Pkinase
CNH
Pkinase_Tyr
NM_145686 NP_663719     Pkinase
CNH
Pkinase_Tyr
NM_145687 NP_663720     Pkinase
CNH
Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF096300 AAD16137 O95819 EC 2.7.11.1
BC156089 AAI56090    
BC156887 AAI56888    
AY212247 AAO32626 O95819 EC 2.7.11.1
AY834276 AAV97884 Q5MD60  
AB014587 BAA31662 O95819 EC 2.7.11.1
AB013385 BAA33714 O95819 EC 2.7.11.1
AK000380 BAA91127 Q9NX89  
AK295610 BAH12124 B7Z388  
AK296396 BAH12341 B7Z3V5  
AL137755 CAB70907 O95819 EC 2.7.11.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MAP4K4 NP_663719 M.musculus Map4k4 26921 Gene Info NP_032722 95
R.norvegicus Map4k4 301363   NP_001100374 94
D.melanogaster msn 44030   NP_995974 57
A.gambiae AgaP_AGAP006340 1276946   XP_001688845 54

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta