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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. NSF, N-ethylmaleimide-sensitive factor
Sequence ID:NM_006178
NR_040116
Entrez Gene ID:4905
Ensembl ID:ENSG00000073969

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 44668099 - 44834828

 Exon Info From UCSC:
NM_006178

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4812117Full LengthBC030613N-ethylmaleimide-sensitive factor
3939600IncompleteBC013314N-ethylmaleimide-sensitive factor

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006169  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_006178 NP_006169 P46459 EC 3.6.4.6 AAA
CDC48_N
CDC48_2

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U03985 AAA17411 P46459 EC 3.6.4.6
AF102846 AAF04745 P46459 EC 3.6.4.6
AF135168 AAF70545 P46459 EC 3.6.4.6
U80997 AAG23890 Q9H3V6  
BC013314 AAH13314 Q96D47  
BC030613 AAH30613 P46459 EC 3.6.4.6
AK290204 BAF82893 P46459 EC 3.6.4.6
AK294001 BAG57363 B4DFA2  
AK294727 BAG57874 B4DGR3  
AK294886 BAG57980 B4DH19  
AK299786 BAG61667 B4DSK5  
AK299031 BAH12933 B7Z5J7  
AK316057 BAH14428 B7Z9U2  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens NSF NP_006169 R.norvegicus Nsf 60355   NP_068516 98
M.musculus Nsf 18195 Gene Info NP_032766 98
A.gambiae AgaP_AGAP012684 1268587   XP_307148 64
D.melanogaster Nsf2 41694   NP_788676 64
D.melanogaster comt 47091   NP_524877 63
C.elegans nsf-1 266842   NP_001076603 55
S.pombe sec18 2542410   NP_594690 51
S.cerevisiae SEC18 852372   NP_009636 48
N.crassa NCU03387 3872981   XP_956834 48

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta