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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PLCB1, phospholipase C, beta 1 (phosphoinositide-specific)
Sequence ID:NM_015192
NM_182734
RefSeqGene ID:NG_028168
Entrez Gene ID:23236
Ensembl ID:ENSG00000182621

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 12 

Cytogenetic Location (from UniGene)

Cytogenetic Location:20p12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:20: 8112911 - 8865550

 Exon Info From UCSC:
NM_015192
NM_182734

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
7262405Full LengthBC069420phospholipase C, beta 1 (phosphoinositide-specific)
40125782Full LengthBC117231phospholipase C, beta 1 (phosphoinositide-specific)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_056007  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_015192 NP_056007 Q9NQ66 EC 3.1.4.11 C2
PI-PLC-Y
PI-PLC-X
NM_182734 NP_877398      

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AY004175 AAF86613 Q9NQ66 EC 3.1.4.11
BC069420 AAH69420 Q9NQ66 EC 3.1.4.11
BC117231 AAI17232 Q9NQ66 EC 3.1.4.11
HQ258537 ADR83291    
AB011153 BAA25507 Q9NQ66 EC 3.1.4.11
AK023689 BAB14641 Q9NQ66 EC 3.1.4.11
AK127693 BAG54550 B3KXN8  
AK299195 BAG61238 B4DRC6  
AL137267 CAB70666 Q9NQ66 EC 3.1.4.11
AJ278313 CAB98142 Q9NQ66 EC 3.1.4.11
AJ278314 CAB98143 Q9NQ66 EC 3.1.4.11

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PLCB1 NP_056007 M.musculus Plcb1 18795 Gene Info NP_001139302 97
R.norvegicus Plcb1 24654   NP_001071109 97
A.gambiae AgaP_AGAP009115 1280066   XP_319865 46
D.melanogaster Plc21C 33204   NP_995604 44

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta