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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. IQGAP1, IQ motif containing GTPase activating protein 1
Sequence ID:NM_003870
Entrez Gene ID:8826
Ensembl ID:ENSG00000140575

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:15q26.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:15: 91017191 - 91017917

 Exon Info From UCSC:
NM_003870

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9007269Full LengthBC151834IQ motif containing GTPase activating protein 1
40073370Full LengthBC139731IQ motif containing GTPase activating protein 1
3852746IncompleteBC020549IQ motif containing GTPase activating protein 1
4065996IncompleteBC016714IQ motif containing GTPase activating protein 1
4272972IncompleteBC005906IQ motif containing GTPase activating protein 1
5539472IncompleteBC037425IQ motif containing GTPase activating protein 1
6014074IncompleteBC110811IQ motif containing GTPase activating protein 1
6150095IncompleteBC064971IQ motif containing GTPase activating protein 1
6185052IncompleteBC089385IQ motif containing GTPase activating protein 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003861  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_003870 NP_003861 P46940 CH
WW
IQ
RasGAP
RasGAP_C

Related Sequences

 
mRNAGenPeptSwissProt
BC005906 AAH05906 Q05DN7
BC020549 AAH20549 Q6P1N4
BC037425 AAH37425 Q6P1N4
BC064971 AAH64971 Q6P1N4
BC089385 AAH89385 Q5FWG8
BC110811 AAI10812 Q6P1N4
BC139731 AAI39732 A4QPB0
BC151834 AAI51835 P46940
AF401205 AAL02166 Q96PA3
D29640 BAA06123 P46940
AK298000 BAG60306 B4DNP4
AK304337 BAG65182 B4E2M0

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens IQGAP1 NP_003861 M.musculus Iqgap1 29875 Gene Info NP_057930 96
R.norvegicus Iqgap1 361598   NP_001101959 96

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)