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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. GNB1, guanine nucleotide binding protein (G protein), beta polypeptide 1
Sequence ID:NM_002074
Entrez Gene ID:2782
Ensembl ID:ENSG00000078369

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:1p36.33Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 1717252 - 1721894

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2964393Full LengthBC004186guanine nucleotide binding protein (G protein), beta polypeptide 1
3605228Full LengthBC005888guanine nucleotide binding protein (G protein), beta polypeptide 1
4155946Full LengthBC008991guanine nucleotide binding protein (G protein), beta polypeptide 1
40032959IncompleteBC114618guanine nucleotide binding protein (G protein), beta polypeptide 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002065  

Protein Infomation

NM_002074 NP_002065 P62873 WD40

Related Sequences

M36430 AAA63265 P62873
AF070597 AAC28652 Q71UM7
AF070603 AAC28655 Q71UM6
BC004186 AAH04186 P62873
BC005888 AAH05888 P62873
BC008991 AAH08991 P62873
BC114618 AAI14619 Q1RMY8
AF501882 AAM15918 P62873
BT007305 AAP35969 P62873
AK312614 BAG35501 B2R6K4
AK122949 BAG53814 B3KVK2
X04526 CAA28207 P62873
CR456784 CAG33065 P62873

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens GNB1 NP_002065 M.musculus Gnb1 14688 Gene Info NP_032168 100
R.norvegicus Gnb1 24400   NP_112249 100
A.gambiae AgaP_AGAP005911 1276578   XP_315941 86
C.elegans gpb-1 174803   NP_496508 86
A.gambiae AgaP_AGAP005912 1276579   XP_315942 85
D.melanogaster Gbeta13F 32544   NP_525090 84
N.crassa NCU00440 3872842   XP_956704 66

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)